Category: Science News
Tags: AIAspirinCancerResearchTurbines
Entities: AspirinDivia TyagiMicrosoftMustafa SulanNatureOpenAIPerplexityUniversity of Cambridge
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welcome to discover daily by perplexity your AIC curated digest of breakthroughs in Tech science and culture my name's Ally today we're exploring how aspirin might be a powerful tool in the fight against cancer but first let's look at
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what else is happening across the tech and science landscape Microsoft is making moves to diversify its AI strategy Beyond its close partnership with open AI the tech giant is developing its own AI models particularly the maai family which have
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shown promising results in recent tests these models are being considered as potential replacements for open AI technology in Microsoft's co-pilot AI assistance Microsoft's maai models have performed nearly as well as leading
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models from open Ai and anthropic on commonly accepted benchmarks the company is also creating its own AI reasoning models comparable to open AIS designed to handle complex queries and display human-like problemsolving abilities this shift in strategy comes under the
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leadership of Mustafa sulan who joined Microsoft last year as the head of its AI division sulan co-founder of Deep Mind and former CEO of inflection AI has been instrumental in pushing for greater independence from open AI Microsoft is not just focusing on in-house
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development the company is also exploring collaborations with other AI companies like xai meta and deep seek this diversification aims to reduce Reliance on open AI and maintain a Competitive Edge in the rapidly evolving AI landscape while
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Microsoft remains a major investor in open AI this strategic move signals a shift in the Dynamics between the two companies it raises questions about the future of their collaboration and the potential impact on existing products that rely on open AIS technology moving on to our Second Story
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a graduate student at Penn State University has refined a century old mathematical problem in wind turbine aerodynamics potentially advancing wind energy science and turbine design efficiency Divia tyagi's groundbreaking research published in wind energy
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science presents an amendment to Herman Glow's Optimum rotor disc solution from the 1920s tyagi's work offers an alternative mathematical approach using calculus of variations and provides analytical solutions for thrust and bending moment coefficients in other
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words tyagi's new method gives clear formulas for measuring how forces affect structures making it easier to understand than previous approaches this comprehensive mathematical model provides a more realistic depiction of turbine Dynamics it expands on Glow's original focus by
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incorporating total force and moment coefficients acting on the rotor as well as how turbine blades Bend under wind pressure tyagi's research introduces a novel approach to solve for optimal flow conditions recovering Glow's original distributions for axial and angular
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induction factors her work also reveals finite non-zero values for thrust and bending moment coefficients as tip speed ratio approaches zero more simply tagi found a better way to figure out how wind should flow through turbines while
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also showing that even when turbine blades are barely moving they still experience forces that can push and bend them the Practical implications of this refinement are significant even a 1% increase in power coefficient for large wind turbines could translate to
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substantial gains in energy output potentially powering entire communities this advancement could lead to more efficient turbine designs and increased energy production from existing wind
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farms now let's dive into our main story of the day a significant study from the University of Cambridge published in nature has uncovered how aspirin could play a role in preventing cancer from spreading the research reveals that
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aspirin enhances the immune systems ability to Target and combat metastatic cells this breakthrough not only highlights aspirin's potential as a cancer fighting medication but also paves the way for creating more precise therapies aimed at halting cancer
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metastasis aspirin's cancer fighting potential stems from its ability to decrease thromboxane A2 production a clotting Factor produced by platelets in the bloodstream thromboxane A2 normally activates a protein called a rhg ef1 in
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te- cells suppressing their ability to identify and eliminate metastatic cancer cells by reducing thromboxane A2 levels aspirin effectively releases tea cells from this suppression enabling them to recognize and attack cancer cells before
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they establish metastatic tumors Dr Jayy one of the researchers described this discovery as a Eureka moment to demonstrate aspirin's Effectiveness researchers used a mouse model of melanoma mice treated with Aspirin exhibited significantly fewer metastases
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compared to control subjects this reduction in cancer spread was directly linked to aspirin's ability to prevent thromboxane A2 from impairing te- cell function Professor Rahul Roy chud huri who led the study emphasized a critical
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therapeutic window of opportunity when cancer cells are particularly vulnerable to immune attack this finding could be crucial in developing targeted therapies to prevent cancer metastasis building on This research the ad aspirin clinical trial aims to determine if aspirin can stop or delay
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the recurrence of early stage cancers this trial follows previous large randomized controlled studies that unexpectedly found lower cancer mortality rates among daily aspirin users but aspirin can cause serious side effects in some individuals including bleeding and stomach ulcers researchers
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emphasize the importance of Consulting a doctor before starting any aspirin regimen looking ahead this discovery opens up exciting possibilities for future Cancer Treatments researchers are exploring the potential of aspirin or other drugs targeting the thromboxane A2
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pathway as more affordable alternatives to anybody based therapies as metastasis is responsible for approximately 90% of cancer related deaths worldwide this breakthrough could lead to significant advancements in cancer prevention and treatment strategies particularly in
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addressing the critical early stages of metastasis that's all for today's episode of discover daily before we conclude a brief note on
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stories that shape our world until then stay curious [Music]