🚀 Add to Chrome – It’s Free - YouTube Summarizer
Category: N/A
No summary available.
00:00
let's talk about youthfulness of skin or the appearance of youthfulness in skin what to do what to buy or not buy as the case may be to try and reverse aging or the appearance of Aging in skin or even create denovo new synthesis of collagen
00:16
and skin to make skin look more [Music] youthful let's talk about where there is a lot of evidence for certain things that you can do if your goal is to increase the youthfulness or the appearance of Youth in your skin and one of the main ones is collagen itself as
00:33
you know there are various macronutrients present in foods you can have proteins fats and carbohydrates when we ingest proteins such as beef chicken fish eggs they contain different amounts of different essential amino acids and those essential amino acids
00:48
are used as the building blocks for proteins in our muscles in our tendons in essentially all the organ systems of our body what most people in the field of nutrition agree upon and what certainly I believe is that if you were to say eat a little bit of liver right you might have a little bit of cooked
01:04
liver that there's no selective trafficking of the amino acids that are broken down from the liver that you eat to your liver however when we talk about collagen this protein that forms one of the most essential aspects of what makes our skin what it is which is elastic why
01:19
would ingesting collagen be selectively trafficked to the collagen in our skin that doesn't square with everything we know and yet when you look at studies including meta anal analyses of studies where people supplement with collagen powders and these powders typically come from fish or Tender any number of
01:36
different sources you often will find studies that show statistically significant improvements in collagen composition and skin appearance and even the appearance of reduction in wrinkles and so forth so this is an interesting exception where the ingestion of a particular protein that naturally exists
01:52
in abundance in certain tissues such as Skin but also other tissues like tendon ligaments Etc seems to be assist in either the repair and Rejuvenation of collagen or perhaps some other aspect of collagen synthesis that leads to
02:08
improvements in collagen composition and the appearance of skin in humans the basic takeaway of this and other metaanalyses is that when people supplement with anywhere from 5 to 15 G okay grams of hydroly collagen per day in particular in combination with
02:24
vitamin C it doesn't have to be a lot of vitamin C that one can observe okay not always but can observe OB erve some visible improvements in skin composition meaning less wrinkles even some reversal of wrinkles less skin sagging more youthful appearance more let's just call
02:40
it uh rebound elasticity of the skin I realize that's not the appropriate technical term but uh the ability of a skin to bounce back from an indentation when you push down on it as opposed to saying down or or sagging so some pretty impressive results when one considers that what people are basically doing
02:56
here is just mixing up some hydrolized collagen protein and then drinking that down once per day or so now that is not to say that you have to supplement with hydrolized collagen why well collagen is also present in various Foods so for instance drinking bone broth beef bone
03:12
broth chicken bone broth is a rich source of collagen you can go online and simply look up just by web search you can just say you know what foods contain high levels of collagen and you'll get a list of things back there hopefully a few of those are not just palatable to you but you actually like and you can start to include those in your daily
03:27
diet or you could supplement with IED collagen protein there any number of different sources for these for those of you that are interested in ingesting collagen peptides as a way to improve the youthfulness of your skin should mention that the dosages there come in a Range depending on the studies that you've looked at and the dermatologist
03:43
that I spoke to said if one decides to go down this route of supplementing or getting collagen from food sources you want to aim for anywhere from 15 gram to 30 gram of collagen peptides per day okay that's a bit higher than what was used in a number of uh studies but
03:59
you'll find studies that use 30 G and that that whole process can be augmented can be improved through ingestion of 500 to 1,000 milligrams of Vitamin C as well but check the label on those collagen peptides that you might be supplementing with because often times they already
04:15
include that 500 to 1,000 milligrams of Vitamin C what about other peptides okay so this is a big topic nowadays especially in the online communities there are lots of things that qualify as peptides but these these days when you hear about
04:30
quote unquote peptides especially in online communities generally people are referring to exogenously given so pills ointments or more typically injections of peptides that are designed to achieve some specific biological or physiological outcome and one of the more common of these peptides being used
04:47
nowadays is one that I've talked about before called bpc157 body protection compound 157 it's known that certain peptides within the gut that bpc 157 is known to mimic can assist in tissue and wound repair of different kinds tendon anything involving fiber blast all of
05:02
that has been well demonstrated in vitro in a dish okay so not in Vivo as well as in Vivo in certain cases but only in animal models to my knowledge there's only one study and frankly it's not a very good study at all on bpc157 in humans and yet a lot of people are
05:18
taking bpc157 either orally in the form of a capsule or pill or more typically injecting it what does it do or what does it likely do in humans we know from animal models that bpc157 increases angiogenesis the growth of capillaries in blood vessels we know this it can
05:33
accelerate wound healing by virtue of increasing fibr blast motility for this reason it's used post injury in sports it's used by people who want to build more muscle it's used by endurance athletes it's used for cosmetic purposes anytime people are using bpc157 for any
05:50
of those purposes it's likely that they're using it in part to increase the blood flow that's available to a given tissue and the repair of that tissue now again I do want to caution people that there is very little basically no evidence in humans besides the anecdotal evidence that people say they healed
06:06
faster what I do know is that anytime you get vascularization of tissue you're going to get improved blood flow so it all makes sense mechanistically I also know that vascularization due to bpc157 is likely to occur globally throughout the body that also tells us that there's going to be increased vascularization of
06:22
other tissues such as Skin such as tumors if tumors exist so you need to be very careful I need to say that upfront as a cautionary note more and more products are out there that contain bpc-157 I can't in good conscious recommend those products I can only offer to you the likely mechanism by
06:38
which they work if they work the logic would be that if you take a cream containing bpc157 and you put it on there that you'll get increased vascularization of that area delivery of more growth factors in nutrients and those wrinkles will either be halted in their aging progression or that they
06:54
will reverse that's the logic many of the products that contain bpc157 by the way all o contain copper copper is a trace mineral it's found in your diet there is some evidence that copper is important for some of the collagen and other elements of skin synthesis
07:09
Pathways and so the mechanistic logic and the biochemical logic is there on paper copper has been shown to play a key role in DNA repair which is a critical component of the turnover of collagen and other proteins in skin it has been shown to reduce so-called reactive oxygen species so it serves as
07:26
a so-called antioxidant but too much copper is a problem so I wouldn't run out and start supplementing with excessive amounts of copper please don't do that but you want to make sure that you're getting sufficient amounts of copper from your diet and you can simply look up online what sufficient amounts of copper are given it's a trace mineral and it's very likely that if you ingest
07:42
any kind of supplement that is a multivitamin mineral supplement or a foundational nutrition supplement that includes at least some copper so it's likely that you're sort of quote unquote topped off in terms of the amount of copper that you need but very unlikely to be excessive amounts of copper but if you start supplementing with copper
07:58
beyond that again can induce an inflammatory response so it's a dosage uh kind of Middle Ground issue there you don't want your copper too low you don't want your copper too high you want it right there in the middle so when I spoke to board certified dermatologists what people can
08:14
do to improve the youthfulness or the appearance of youthfulness In Their Skin they mentioned supplementing with niacinamide niacinamide is a form of vitamin B3 it is also sometimes referred to as nicotinamide and I was told that when taken at twice per day at a dosage of 500 Mig per dose for a total of 1 gr
08:32
or 1,000 Mig per day that niacinamide supplementation can increase the production of ceramides which relate to the lipids in skin that improve the moisture in skin and by the way moisture in skin is a key component of the youthfulness or plump appearance of that
08:48
skin and when I say plump I don't necessarily mean outwardly rounded plump I mean the fact that the skin looks like the outermost layer of the skin which you now know as the epidermis is kind of taut and the skin looks hydrated and smooth at the level of its outer appearance all of that is improved by
09:04
niacinamide supplementation but that the supplementation has to be carried out for 3 to 6 months or more before that effect is noticed now the origin of the niacinamide effect on the youthfulness of skin could also be related to the fact that there's evidence that niacinamide supplementation can reduce
09:19
inflammation of skin overall we haven't talked so much about the immune skin relationship but for those of you suffering from rosacea from acne nicomide supplement ation may also assist there regardless of whether or not you suffer from rosacea acne or not at all nicomide supplementation May
09:36
benefit you also because nicomide supplementation appears to balance the level of oil production in the skin you need oil in the skin you need oil down in those pores but not too much it can definitely help reduce the appearance of clogged pores and if you're concerned about pores that appear too large this
09:51
typically happens in the face around the nose on the upper cheeks although other regions of the body as well nicomide supplementation May assist with that as well there's also a number of people out there that are concerned with specific spots that they see as hyperpigmented spots so regardless of whether or not
10:07
overall your skin is very light or very heavily pigmented supplementation with niacinamide can reduce the appearance of accumulation and maybe even the actual accumulation of melanin at particular spot so-called dark pigmented spots that some people decide that they don't want
10:22
for whatever reason usually just cosmetic reasons now if you decide to supplement with niacinamide you have the option of either taking that 1,000 milligrams and 2 500 milligram dosages per day you also have the option of using any number of different topical niacinamide ointments or serums that
10:37
exist out there keep in mind that many skincare products already contain niacinamide so check the label and there the dermatologists tell me that to be effective the niacinamide needs to be present at at least a two and as high as 10% concentration within those ointments or serums
10:54
[Music]